An antibacterial agent designed to manage inflammatory skin conditions and utilized to treat specific chronic infections like leprosy to alleviate progression.
Mechanism of Action
It works as an antibacterial by inhibiting the synthesis of dihydrofolic acid in bacteria. It also has anti-inflammatory properties that suppress the activity of certain white blood cells in the skin.
Route of Administration
Oral
Onset Time
Several weeks
Duration
24 hours
Contraindications
Severe anemia, Allergy to dapsone or sulfones
Severe Adverse Events
Hemolysis (breakdown of red blood cells), Liver damage, Severe skin reactions, Agranulocytosis
Common Side Effects
Headache, Nausea, Loss of appetite
Uncommon Side Effects
Skin rash, Dizziness, Anemia, Insomnia
Drug Interactions
Rifampin, Trimethoprim, Probenecid, Zidovudine
Pregnancy Safety Warnings
Generally used only if benefits outweigh risks; monitor for neonatal hemolysis.
Information for Dapsone is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.
