Utilized to manage blood sugar and address heart and kidney risks to alleviate metabolic strain and support improved cardiovascular health in adult patients.
Mechanism of Action
Dapagliflozin inhibits the SGLT2 protein in the kidneys. By preventing the reabsorption of glucose into the bloodstream, it causes excess sugar to be removed from the body through the urine, which also helps reduce blood pressure.
Route of Administration
Oral
Onset Time
Steady state in 2 days
Duration
24 hours
Contraindications
Severe renal impairment (specific stages), Dialysis, History of hypersensitivity, Type 1 diabetes
Severe Adverse Events
Diabetic ketoacidosis, Severe kidney injury, Fournier's gangrene, Urosepsis, Severe dehydration
Common Side Effects
Increased thirst, Increased urination
Uncommon Side Effects
Urinary tract infections, Genital yeast infections, Nausea, Dizziness, Back pain
Information for Farxiga is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.