A clinical formulation indicated for Skin Care. Application assists with the management of actinic keratosis and superficial basal cell carcinoma by inhibiting abnormal skin cell growth.
A topical chemotherapy agent utilized to manage precancerous skin lesions and designed to alleviate early skin cancers by targeting abnormal cell growth.
Mechanism of Action
It interferes with the synthesis of DNA and RNA in rapidly dividing cells. Since cancer cells grow faster, they are selectively destroyed by the drug.
Route of Administration
Topical
Onset Time
Visible reaction in 3–5 days
Duration
2–4 weeks
Contraindications
DPD enzyme deficiency, Pregnancy, Allergy to fluorouracil
Severe Adverse Events
Severe skin ulceration, Liver toxicity (if absorbed), Low white blood cell count, Anaphylaxis
Common Side Effects
Skin redness, Burning sensation, Itching
Uncommon Side Effects
Skin crusting, Scabbing, Soreness, Swelling, Increased sensitivity to light
Drug Interactions
Warfarin
Pregnancy Safety Warnings
Contraindicated; can cause severe birth defects.
Age Restrictions
Safety in children not established.
Storage Guidelines
Store at room temperature. Wash hands immediately after use.
Information for Fluorouracil is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.
