A clinical formulation indicated for Heart and Blood Pressure. Vessel-dilating properties support better blood flow and assist in reducing the frequency of angina episodes.
Intended to address chronic chest pain by targeting arterial dilation to alleviate cardiac workload and support healthy oxygen flow to the heart muscle effectively.
Mechanism of Action
This medication is converted into nitric oxide, which causes the smooth muscles in the blood vessel walls to relax. This widens the arteries, lowering blood pressure and making it easier for the heart to pump.
Route of Administration
Oral
Onset Time
30–60 minutes
Duration
12–24 hours (ER form)
Contraindications
Concurrent use of PDE5 inhibitors, Severe anemia, Hypersensitivity to nitrates, Low blood pressure, Shock
Severe Adverse Events
Severe hypotension, Fainting, Severe chest pain worsening, Severe allergic reactions, Methemoglobinemia
Common Side Effects
Flushing, Mild dizziness
Uncommon Side Effects
Headache, Dizziness, Nausea, Low blood pressure, Fast heartbeat
Drug Interactions
Sildenafil, Tadalafil, Alcohol, Alpha-blockers, Other antihypertensives
Pregnancy Safety Warnings
Use only if benefit justifies potential risk to the fetus.
Information for Isosorbide is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.
