A broad-spectrum antifungal intended to manage systemic and nail fungal infections to alleviate symptoms and target complete clearance of the organism.
Mechanism of Action
It inhibits the fungal cytochrome P450-dependent enzyme lanosterol 14α-demethylase. This stops the production of ergosterol, a vital component of the fungal cell membrane.
Route of Administration
Oral
Onset Time
Variable
Duration
Weeks to months
Contraindications
Heart failure, Use of certain statins (Lovastatin, Simvastatin), Pregnancy, Liver disease
Severe Adverse Events
Congestive heart failure, Liver failure, Hearing loss, Severe skin reactions
Information for Itraconazole is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.