A clinical formulation indicated for Heart and Blood Pressure. This treatment relaxes blood vessel walls, assisting in the reduction of pulmonary vascular resistance for improved cardiovascular function.
Designed to alleviate pulmonary hypertension symptoms by addressing vessel narrowing to support physical capacity and mitigate disease progression in adult patients effectively.
Mechanism of Action
Ambrisentan blocks receptors for endothelin, a natural substance that causes blood vessels in the lungs to constrict. By blocking these receptors, it allows the vessels to relax and widen, lowering lung blood pressure.
Route of Administration
Oral
Onset Time
Steady state in 2 days
Duration
24 hours
Contraindications
Pregnancy, Idiopathic pulmonary fibrosis, Severe liver impairment, Hypersensitivity to ambrisentan
Information for Letairis is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.
