Ofev
Ofev

3.9
A clinical formulation indicated for Asthma and Breathing. Facilitates the slowing of progressive lung scarring while supporting overall respiratory capacity.


Availability
In Stock
Delivery Time
Airmail (14-21 days) | Trackable (5-9 days)
Shipped in a discreet, unmarked envelope with all required documents enclosed.

Product Sheet

Active Ingredient(s)
Nintedanib Esylate
Reference Brand
Nintedanib
Product Origin
Generic Alternative
Reference Manufacturer
Boehringer Ingelheim
Product Form
Capsule
Regulatory Classification
Rx
Primary Category
Respiratory Health
Product Category
Antifibrotic
Pharmacological Class
Tyrosine Kinase Inhibitor
Manufacturer Description
Indicated to address lung scarring progression to alleviate respiratory decline and support improved oxygen capacity in patients with chronic fibrosing lung conditions.
Mechanism of Action
Nintedanib blocks receptor tyrosine kinases that trigger the growth and activation of lung fibroblasts. By inhibiting these pathways, it slows the excessive scarring of lung tissue that makes breathing difficult.
Route of Administration
Oral
Onset Time
Variable; months for clinical change
Duration
12 hours
Contraindications
Severe liver impairment, Hypersensitivity to peanut or soya, Pregnancy
Severe Adverse Events
Severe liver injury, Gastrointestinal perforation, Arterial thromboembolic events, Serious bleeding, Heart attack
Common Side Effects
Mild abdominal pain, Decreased appetite
Uncommon Side Effects
Diarrhea, Nausea, Vomiting, Weight loss, Increased liver enzymes, Headache
Drug Interactions
Ketoconazole, Rifampin, Carbamazepine, Anticoagulants
Pregnancy Safety Warnings
Contraindicated; can cause fetal death or severe harm.
Age Restrictions
Safety not established in children.
Storage Guidelines
Store below 25°C in a dry place.
Related Products
Information for Ofev is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.
Categories