A nucleotide analogue intended to manage Hepatitis C infection and designed to alleviate liver inflammation by targeting viral replication to support patient recovery.
Mechanism of Action
It inhibits the Hepatitis C virus NS5B RNA-dependent RNA polymerase, which is the enzyme the virus needs to duplicate its genetic material.
Route of Administration
Oral
Onset Time
Steady state in days
Duration
24 hours
Contraindications
Allergy to sofosbuvir
Severe Adverse Events
Hepatitis B reactivation, Severe bradycardia (with amiodarone), Liver failure, Severe allergic reaction
Common Side Effects
Fatigue, Headache
Uncommon Side Effects
Nausea, Insomnia, Anemia, Pruritus (itching)
Drug Interactions
Amiodarone, Rifampin, Carbamazepine, St. John's wort, Phenytoin
Information for Sovaldi is sourced from established medical standards and updated frequently. It is provided for general reference and should be confirmed with a healthcare professional before use.
